Is psoriasis caused by an overactive immune system?
At a basic level, psoriasis is a disorder of the immune system. White blood cells called T-helper lymphocytes become overactive, producing excess amounts of cytokines, such as tumor necrosis factor, interleukin-2, and interferon-gamma. In turn, these chemicals trigger inflammation in the skin and other organs.
What does psoriasis do to your immune system?
When the immune response of the body is triggered in cases of psoriatic disease, it can lead to inflammation that can cause skin and/or joint symptoms to flare (sudden start or worsening of symptoms), along with systemic inflammation that can affect other parts of the body.
What is the life expectancy of someone with psoriasis?
When you start layering all of those comorbid conditions with psoriasis, then, in people who have early age of onset of psoriasis, the loss of longevity may be as high as 20 years. For people with psoriasis at age 25, it’s about 10 years.”
Can psoriasis be a symptom of something else?
Because psoriasis can look like other skin conditions that cause scaly patches and itchy rashes with inflammation, it is often confused with various disorders. These may include common skin conditions such as acne, eczema, or heat rash.
What is the root cause of psoriasis?
Psoriasis is caused, at least in part, by the immune system mistakenly attacking healthy skin cells. If you’re sick or battling an infection, your immune system will go into overdrive to fight the infection. This might start another psoriasis flare-up. Strep throat is a common trigger.
Why do I suddenly have psoriasis?
A triggering event may cause a change in the immune system, resulting in the onset of psoriasis symptoms. Common triggers for psoriasis include stress, illness (particularly strep infections), injury to the skin and certain medications.
What organs are affected by psoriasis?
Psoriasis is a disorder of the immune system. It causes white blood cells to become overactive and produce chemicals that trigger inflammation in the skin. This inflammation can also affect other parts of the body, including the lungs.
What happens if psoriasis is left untreated?
Left untreated, patients with moderate-to-severe psoriasis could develop psoriatic arthritis (PsA), which affects up to 40% of patients. Similar to rheumatoid arthritis, PsA can cause pain, disability, and permanent joint deformities.
Is psoriasis a death sentence?
17, 2007 — Psoriasis is not generally thought of as life-threatening, but it just might be for those with the severest forms of the disease. People with severe psoriasis had a 50% increased risk of death compared with people without the inflammatory skin disease in a newly reported study.
Do you get sick more often with psoriasis?
Living with an autoimmune disease
Psoriasis is an autoimmune disease, which means your immune system is in overdrive, attacking otherwise healthy cells and tissue. This type of hyperactivity in the immune system can make people with psoriasis more prone to illness, especially during flu season.
What is the most common cause of psoriasis?
Common psoriasis triggers include: Infections, such as strep throat or skin infections. Weather, especially cold, dry conditions. Injury to the skin, such as a cut or scrape, a bug bite, or a severe sunburn.